Research

Life Sciences & Biotechnology

Title :

Comprehensive understanding of cellular response to amyloid toxicity at molecular level

Area of research :

Life Sciences & Biotechnology

Focus area :

Amyloid toxicity

Principal Investigator :

Dr. Deepak Kumar Sharma, Scientist, Institute of Microbial Technology (IMT), Chandigarh

Timeline Start Year :

2017

Timeline End Year :

2019

Contact info :

Details

Total Budget (INR):

5,42,000

Outcome/Output:

The project will study the genetic manipulation of S. cerevisiae for construction of yeast model of alpha synuclein toxicity. The study will lead to the identification of cellular proteins adversely affected by accumulation of the cystolic alpha synuclein inclusions and identification of cellular factors on alpha synuclein mediated cytotoxicity.

Organizations involved