Research

Chemical Sciences

Title :

Design, and synthesis of Nitrogen-containing Heterocycles and in vitro studies of their Cytotoxic Activity

Area of research :

Chemical Sciences

Principal Investigator :

Dr. Boda sakram, Osmania University, Hyderabad, Telangana

Timeline Start Year :

2023

Timeline End Year :

2026

Contact info :

Equipments :

Details

Executive Summary :

1,8-Naphthyridines have various pharmacological effects, including being effective DNA intercalates. They alter DNA conformation and inhibit DNA duplication, making them potential anti-cancer agents. To develop potent 1,8-naphthyridine derivatives with other substituted derivatives under greener conditions, researchers aim to synthesize these derivatives under in vitro studies and examine their cytotoxic activity under greener conditions.

Total Budget (INR):

27,40,600

Organizations involved