Executive Summary : | Dopamine is a crucial organic chemical that regulates human metabolism and plays a role in the cardiovascular, central nervous, renal, and hormonal systems. It can lead to severe conditions like Parkinson's disease, ADHD, Tourette syndrome, schizophrenia, and bipolar disorder. Monitoring dopamine levels in vivo and in vitro is critical. A team aims to fabricate an electrochemical device using 2D materials to develop a biosensor capable of detecting dopamine levels. The team uses a novel Mxene material with high conductivity and extensive hydrophilic surface area, promising for electrochemical sensing applications. The approach uses 3D printing, which offers cost-effectiveness, reduced waste, and fast production. The 3D macrostructures developed in this study prevent restacking or aggregation of MXene nanosheets, improving surface utilization and sensor electrochemical performance. The resulting sensors demonstrate excellent sensitivity in detecting dopamine with an ultra-low limit of detection. |