Life Sciences & Biotechnology
Title : | Development of therapeutic monoclonal antibodies against Chikungunya virus |
Area of research : | Life Sciences & Biotechnology |
Focus area : | Pharmaceutical Sciences |
Principal Investigator : | Dr. Rajesh Kumar, Indian Institute of Technology(IIT) Roorkee, Uttarakhand (247667) |
Timeline Start Year : | 2024 |
Timeline End Year : | 2026 |
Contact info : | rajesh.kumar@bt.iitr.ac.in,shailly.tomar@bt.iitr.ac.in |
Details
Executive Summary : | The proposal combines the expertise of India's Dr. Rajesh Kumar and Argentina's Dr. Diego E Alvarez, who have 13 years of experience in developing therapeutic monoclonal antibodies against infectious diseases. The team aims to develop reliable methods for mapping antibody specificities and transfer reagents and technical expertise between laboratories. The focus is on the Chikungunya virus, a major health concern in both countries, and the potential role of neutralizing antibodies (NAbs) in immunotherapy. The proposal will use a recombinant phage display approach to isolate monoclonal antibodies against the virus's E2 protein. |
Co-PI: | Dr. Shailly Tomar, Indian Institute of Technology(IIT) Roorkee, Uttarakhand (247667) |
Total Budget (INR): | 8,18,000 |
Organizations involved