Executive Summary : | Photoredox catalyzed synthetic transformations often use organic dyes/sensitizers and metal complexes as catalysts to harness visible light energy into chemical energy. Diazo compounds have been extensively used as building blocks and surrogates of carbenes in organic synthesis. However, their potential reactivity to generate free radical and triplet spin states has not been reported yet. This project proposal aims to develop efficient photoredox catalyzed synthetic transformations using the potentials of arylidene diazosuccinimides to generate radical and triplet carbene sensitizer-free via direct photoinduced transformations. The project aims to explore the radical reactivity of diazo compounds under visible light irradiation and successfully combine visible-light photocatalysis with earth abundant transition metal catalysis to enable the development of unknown synthetic transformations. The project has already made progress in synthesis of various pyromellitic diimide (PMDI) based luminophors, bioactive organic compounds, and advanced photoredox pathways such as Hydrogen Atom Transfer (HAT), Single Electron Transfer (SET), and Proton-Coupled Electron Transfer (PCET) processes over diazosuccinimides. The project outcome will lead to the development of newer sustainable synthetic protocols, new understanding of carbenes, and insights into mechanistic pathways in the field of visible light photo catalysis and diazo compounds. |