Research

Life Sciences & Biotechnology

Title :

Organoid models for biomedical research applications

Area of research :

Life Sciences & Biotechnology, Medical Sciences

Focus area :

Stem cells

Principal Investigator :

Dr P Chandra Shekar, Scientist, CSIR-Centre for Cellular and Molecular Biology (CSIR-CCMB), Hyderabad

Timeline Start Year :

2020

Timeline End Year :

2025

Contact info :

Details

Executive Summary :

Objective: Derivation and characterization of normal and patient specific iPSCs. . Generation and characterization of CRISPR based fluorescent tracer iPSC lines for lineage tracing. Establishment, improvisation of processes and characterization of brain organoids. Establishment of processes and characterization of trophoblast organoids from pluripotent cells. Establishment and characterization of intestinal organoids from pluripotent cells. Establishment and characterization of optic vesicles. The optic cup organoids will contain the retina.

Organizations involved