Communication Engineering
Title : | Surface Engineering of Biomedical Implants for the Prevention of MDR Infection |
Area of research : | Communication Engineering, Computer Sciences and Information Technology |
Focus area : | Antimicrobial Strategies |
Principal Investigator : | Dr. Selvakumar Murugesan, National Institute Of Technology, Mangalore, Karnataka, 575025 |
Timeline Start Year : | 2023 |
Timeline End Year : | 2026 |
Contact info : | murugesan_selva@nitk.edu.in |
Details
Executive Summary : | Bacterial infections in biomedical implants cause severe damage and lead to implant failure, surgery, and re-implantation. Current antibiotics are ineffective due to their limited ability to reach damaged tissue, MDR development by bacteria, and toxic side effects. A new project aims to develop a novel coating formulation using natural polyphenol tannic acid, engineered spider silk protein, and 2D-nanomaterial MXenes for synergistic triple-mode antibacterial action. The formulation will be extended to scaffolds and studied for biofilm formation and antimicrobial characteristics using various assays. This will lead to a universal low-cost coating technology for various medical substrates. |
Total Budget (INR): | 44,34,400 |
Organizations involved