Research

Medical Sciences

Title :

Surface-modified porous Ti-based implants produced by additive methods for cranio-maxillofacial and dental surgery

Area of research :

Medical Sciences

Focus area :

Biomedical Engineering and Materials Science

Principal Investigator :

Dr. B Subramanian, CSIR- Central Electrochemical Research Institute (CERI), Karaikudi, Tamilnadu (630003)

Timeline Start Year :

2023

Timeline End Year :

2026

Contact info :

Details

Executive Summary :

The increasing demands for medical goods and supplies have led to a rise in the production of implants to replace injured areas. The global metal implants and metallic alloy devices market is expected to grow significantly, with a net worth of 12.55 billion in 2020 and 27.43 billion in 2027. These bio-inert materials are used in joint replacements, orthopedic fixators, and dental implantable screws. They are categorized based on titanium, cobalt, and ferrous-based alloying materials. The main disadvantage of metallic implants is the release of toxic ions, which can cause inflammation, allergic reactions, or cell death. To address this, surface modification of metallic implants is proposed. Techniques such as sputtering, electrophoretic deposition, and plasma electrolytic oxidation (PEO) can be used to enhance the bio affinity of osseointegeration. The development of effective and reliable technology for modifying the surface of metal implants is crucial for reducing microbial infection associated with the replacement of damaged bone tissue. This project aims to propose different strategies for modifying the surface of metallic implants to improve their osseointegeration with bone tissue and suppress infection in the implantation zone. The project involves fabricating a bio ceramic layer onto 3D printed dental and cranio maxillofacial implants using magnetron sputtering and electrophoretic deposition. The successful outcome lies in the innovative development of bio ceramic coatings onto 3D printed implantable materials, which improve the strong interface with bone tissue and provide improved regenerative properties for long-term implant consolidation.

Co-PI:

Dr. Murugan Veerapandian, CSIR- Central Electrochemical Research Institute (CERI), Karaikudi, Tamilnadu (630003)

Total Budget (INR):

53,89,383

Organizations involved