Research
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Title : | Synthesis of Porous Multicomponent HOFs for Separation and Sorption |
Area of research : | Chemical Sciences |
Focus area : | Materials Science, Chemical Engineering |
Principal Investigator : | Dr. Srinu Tothadi, CSIR-Central Salt Marine Chemicals Research Institute, Gujarat |
Timeline Start Year : | 2023 |
Timeline End Year : | 2025 |
Contact info : | srinut[dot]iisc[at]gmail[dot]com |
Details
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Executive Summary : | The development of porous multicomponent HOF materials could be the solution for challenging global problems like marine water purification and sustainable energy. Moreover, these materials would be one of the most promising materials for human well-being. MOFs and COF are key crystalline materials and dominate in porous materials due to their extended framework via nodes and linkers (MOF) and covalent bonds (COF). In addition, they allow material for post-synthetic modification. Apart from these crystalline materials, HOFs are another form of crystalline materials where molecules are connected via non-covalent interactions with some extent of microporosity. Multicomponent HOF crystals could have great scope for new porous organic crystalline forms since at least two molecules are present in a stoichiometric ratio, which generally exist as solids at room temperature. Moreover, similar to cocrystal synthesis, multicomponent HOFs could be synthesized via a simple slow evaporation method. High-quality single crystals are characterized by single-crystal diffraction, which is crucial for understanding structure-property elucidation. HOFs are formed by organic building blocks such as hydrogen-bonded or halogen bonded networks in two or three-dimensional networks. Multicomponent HOFs include salts, cocrystals, and solvates. During the last decade, considerable advancement has been made in HOF since the most recent work on porous organic crystalline materials confines to single component crystals of carboxylic acids, urea, diaminotriazine (DAT) and heterocycles. Marsh and Duchamp reported the earliest hydrogen bond framework in 1969 as the 3D structure of trimesic acid, where molecules are extended via acid-acid dimer synthons and crystal packing leaves isolated voids. Recently, Andy and co-workers and we have reported a polymorph of trimesic acid showing almost 50% vacancy in the crystal packing. In all these structures, crystal packing is stabilized by the basic motif of an acid-acid dimer, pi-pi stacking without interpenetration. In the literature, about 3336 acid-pyridines and 494 acid-amide dimers are found. Previously, we designed synthesized cocrystals/salts of acid-amide dimers. Hence, intermolecular interactions can be controlled, and multicomponent HOFs can be synthesized. By using a suitable coformer, we could fine-tune the porosity of the crystalline materials. For instance, recently, single-component porous organic crystalline materials (HOF) were used in catalysis, and biomedical applications and cocrystals (HOF) were used to enhance the therapeutic efficacy of NSC transplantation. Very recently cyano modified tetraphenylethylene has been used for fluorescence applications. Considering the aforementioned applications, our target is to synthesize porous multicomponent HOFs of acid-pyridine and acid-amide and complementary hydrogen-bonded crystalline materials and employ them for suitable applications such as sorption and separation. |
Total Budget (INR): | 29,94,883 |
Organizations involved
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Implementing Agency : | Csir-Central Salt Marine Chemicals Research Institute, Gujarat |
Funding Agency : | Anusandhan National Research Foundation (ANRF)/Science and Engineering Research Board (SERB) |
Source : | Anusandhan National Research Foundation/Science and Engineering Research Board (SERB), DST 2023-24 |